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You mentioned three different endings above, but on the DVD-Case there stands something about 13 different endings. I haven't got to the end so far. Have big trouble with killing the worm in eli's realm. Any hints?
Well, technically, the game has 13 endings, but 11 of them can be grouped into one - the endings are: the player leaves alone, the player helps a sister escape, the player becomes the last keeper of the Void. In the original, there was a possibility to escape together with a sister.
The Worm has quite a lot of hitpoints, but there's a lot of time to kill him, so I'd rather recommend building a war potential for the future Brother encounters on day 23. The leftovers (which you will inevitably have) can be used to net the Shatuns (round potato monsters) with the current double damage color on the wheel. You can actually net only the first Shatun that's always there with 40 drops of lympha in the net. Then blast the worm when it comes out to devour it and add some more damage by the Sleeper of Sentinel.
@Thordax: the worm acts differently from the original.

And doesn't hang.

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How happy is the blameless vestal's lot! The world forgetting, by the world forgot.
Eternal sunshine of the spotless mind! Each pray'r accepted, and each wish resign'd;
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